Dr. Garoli Denis, PhD
Born in Padova, Denis Garoli got a master Degree in Physics at Padova University. He has been awarded a PhD in Space Science and Technology at University of Padova with a thesis on the development of innovative technologies for the environmental conservation. After PhD, He did a Master Degree in Biotechnology at Padova University.
Between 2007 and 2009, He mainly worked on material science R&D for space applications also taking part to a Space Agency’s project (during the collaboration with Media-Lario Technologies – see D. Garoli et al.(2009)). After his first industrial experience Mr. Garoli came back to academic research by collaborating with Laboratory for Nanofabrication of Nanodevices (LaNN - Venetonanotech) and University of Padova and became scientist in charge with Clean Room facilities for nanofabrication. There he extended his view from coatings and material-science to plasmonics and nanotechnologies focusing on nanofabrication and optical applications (see D. Garoli et al. (2012) ; D.Garoli et al. (2013)).
In the end of 2014, he started working as researcher at Istituto Italiano di Tecnologia (IIT) and won the Horizon 2020 FET funding for the project ProseqO (co-coordinator and main WP leader within two italian partners – rank #1 among more than 900 proposals): PROtein SEQuencing using Optical single molecule real-time detection. The project regards the development of new technologies for single molecule detection and manipulation with the final goal of DNA/RNA and protein sequencing. During this period he also, collaborated, coordinated and supported the R&D activities at AbAnalitica in Padova. The main results of the research during these years regard the design, fabrication and test of innovative plasmonic devices for several applications, from material science, to biosensing and optical beam manipulation. During the last two years his activities were focused on nanopore technology for single molecule detection and significant results of the work are now published or under review in high level journals.
Single molecule spectroscopy; nanopores; 2D materials; plasmonics; nanofabrication
Horizon 2020 FET Open ProseqO (2016 - 2019) - Coordinator
The project regards the development of new technologies for single molecule detection and manipulationwith the final goal of DNA/RNA and protein sequencing. In particular, the advent of analytical techniques withextremely low limits of detection has led to dramatic progresses in the field of nucleic acids sequencing. Despitethe development of next generation sequencing platforms, the current genome sequencing task remains formidable, and revolutionary advances in DNA sequencing technology are still demanded. Another technological revolution would be a fast and reliable sequencing of proteins, which are the primary actors invirtually all life processes and are coded by DNA sequences known as genes.